Synthesis and Antiviral activity of some novel diazabicyclo compounds

نویسندگان

  • Chandra Shekhar Sharma
  • Rajesh Kumar Nema
  • V. K. Sharma
  • S. N. Meyyanathan
چکیده

3,5-dinitro-benzoyl chloride was refluxed with different amino acids to form the amino acid derivatives that were reduced with zinc/formic acid, to form the products and the reduced products so formed were cyclized to give the title compounds with benzil in the presence of sodium ethoxide/ethanol. All the intermediates and title compounds were characterized by physical, chemical, analytical and spectral data. All the title compounds were screened for their in-vitro cytotoxic and antiviral activities.

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تاریخ انتشار 2009